Is Zolpidem better than Zopiclone?
Key Takeaways
Zolpidem and Zopiclone are different: Though both medications treat insomnia, they belong to different classes of sedative-hypnotic medications and work in slightly different ways. Zolpidem is faster-acting, while Zopiclone helps keep you asleep longer.
Zolpidem may be better for falling asleep quickly: Zolpidem works faster, making it ideal for those who have difficulty falling asleep but can stay asleep once they doze off.
Zopiclone may be better for staying asleep: Zopiclone is more effective for individuals who can fall asleep easily but struggle to remain asleep throughout the night.
Both Zolpidem and Zopiclone are effective medications prescribed for the treatment of insomnia. However, the question of which is better depends on individual needs and circumstances. In this article, we will compare Zolpidem and Zopiclone, examining how they work, their side effects, and which one might be more suitable for different types of insomnia.
Are Zolpidem and Zopiclone the Same?
While both medications are used to treat insomnia, they are not the same. Zolpidem and Zopiclone belong to the same general class of medications, sedative-hypnotics, but they work in slightly different ways and have different characteristics.
Zolpidem, often branded as Ambien, is a fast-acting medication that helps people fall asleep quickly. In contrast, Zopiclone, also branded as Zimovane, is better suited for people who need help staying asleep throughout the night. Although both are prescribed for the same condition, their use depends on whether the person struggles more with falling asleep or staying asleep.
Comparison: Zolpidem vs Zopiclone
Medication | Price Per Tablet | Strengths | Packet Sizes |
| Zolpidem | From £4.40 | 5mg or 10mg | 10 or 20 tablets |
| Zopiclone | From £4.80 | 3.75mg or 7.5mg | 10 or 20 tablets |
Is Zolpidem Better Than Zopiclone?
The effectiveness of Zolpidem versus Zopiclone depends on the individual’s specific symptoms and needs. Here’s a comparison:
Zolpidem: Typically preferred for those who have difficulty falling asleep but can stay asleep once they do. It is faster acting, with a shorter half-life, meaning it is less likely to cause daytime drowsiness.
Zopiclone: More effective for individuals who fall asleep easily but struggle with staying asleep through the night. It has a longer half-life, which helps maintain sleep throughout the night, but this may also lead to feeling drowsy the following day.
Side Effects of Zolpidem and Zopiclone
Both Zolpidem and Zopiclone share common side effects due to their sedative-hypnotic properties. These include:
Drowsiness during the day
Headaches
Nausea and vomiting
Confusion or memory problems
Some people may experience these side effects more than others. If side effects persist or worsen, it’s important to speak to your doctor. A healthcare professional may recommend adjusting the dosage or switching to a different medication.
Why Would I Use Zolpidem?
Zolpidem is generally prescribed to individuals who struggle with falling asleep quickly. It is fast-acting, and its effects begin within 15 to 30 minutes of taking it, making it ideal for people who need immediate help. Zolpidem is also helpful for those who are sensitive to daytime drowsiness, as its shorter half-life means it’s less likely to cause fatigue the following day.
Why Would I Use Zopiclone?
Zopiclone is ideal for people who can fall asleep but find it difficult to stay asleep. It works more slowly than Zolpidem but has a longer half-life, helping to maintain sleep throughout the night. Zopiclone is also beneficial for people who experience fewer side effects from medications that last longer in the body. However, due to its longer duration, it may cause a hangover effect the next day, including drowsiness and reduced alertness.
What Type of Medication Is Zolpidem?
Zolpidem is a non-benzodiazepine sedative-hypnotic, which means it works by acting on the GABA receptors in the brain to produce a calming effect. Although similar to benzodiazepines in how they work, non-benzodiazepines are generally considered to have a lower risk of dependence and addiction.
What Type of Medication Is Zopiclone?
Like Zolpidem, Zopiclone is a non-benzodiazepine sedative-hypnotic. It works by enhancing the activity of the GABA neurotransmitter, leading to sedation and relaxation. Zopiclone is effective for both helping individuals fall asleep and stay asleep throughout the night.
How Is Zolpidem Taken?
Zolpidem is typically taken as a tablet just before bedtime. You should swallow the tablet with water. Zolpidem works quickly, so you should only take it when you are ready to go to sleep. You can take Zolpidem with or without food, but it’s recommended to avoid alcohol when using this medication. Follow your doctor’s instructions for the correct dosage and duration.
How Is Zopiclone Taken?
Zopiclone is also taken orally, just before bedtime. Like Zolpidem, you should take it with water. If you miss a dose, only take it later in the night if you can get 7-8 hours of uninterrupted sleep. If this isn’t possible, skip the dose and take your next one at the regular time. Zopiclone can be taken with or without food, but it’s important to follow your doctor’s specific instructions.
Final Thoughts
Choosing between Zolpidem and Zopiclone depends on your individual sleep needs. If you have trouble falling asleep, Zolpidem may be a better option. If you struggle with staying asleep, Zopiclone could be more suitable. In either case, it’s crucial to follow your doctor’s advice and never exceed the prescribed dosage. Both medications have side effects, but with proper use and guidance, they can significantly improve sleep quality and overall well-being.
Medically Reviewed by:
Dr. Irfan Siddique MBBS
GMC reference no: 7694522
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