Is it safe to take Zopiclone with other medications?
Key Takeaways
Consult a Doctor First: Zopiclone can interact with several medications, including those for depression, anxiety, epilepsy, and pain relief. Always consult with your healthcare provider before combining Zopiclone with other drugs.
Alcohol and Zopiclone Don’t Mix: Combining Zopiclone with alcohol can significantly increase sedative effects, impairing coordination and increasing the risk of accidents. It’s best to avoid alcohol while taking Zopiclone.
Follow the Prescribed Dosage: Zopiclone is generally safe when used as prescribed. Always follow your doctor’s instructions and avoid self-medication or altering your dosage without professional guidance.
Zopiclone is a popular medication commonly prescribed for the short-term treatment of insomnia. While it can effectively help individuals sleep, it’s crucial to understand how it interacts with other medications. In this article, we’ll explore Zopiclone’s interactions with various substances, including prescription drugs, over-the-counter medications, alcohol, and food. This will help you make informed decisions about using Zopiclone safely.
What is the Active Ingredient in Zopiclone?
The active ingredient in Zopiclone is Zopiclone itself. Zopiclone belongs to a class of drugs known as non-benzodiazepine hypnotics, which work by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA). GABA helps reduce brain activity, producing a calming effect that aids in sleep.
Zopiclone is typically prescribed for short-term insomnia treatment, and doctors generally recommend it for a period of no more than four weeks to avoid dependency and tolerance.
Does Zopiclone Interact with Other Medications?
Yes, Zopiclone can interact with several types of medications. Some combinations may intensify its sedative effects, leading to unwanted side effects such as excessive drowsiness or impaired coordination. Here are some common medication interactions:
Medications that May Interact with Zopiclone
Agomelatine: Can increase sedation, impairing alertness and the ability to perform skilled tasks.
Alfentanil: Both drugs can cause sedation, increasing drowsiness and reducing the ability to concentrate.
Alprazolam: Both medications can cause sedation, which may affect mental clarity and coordination.
Amisulpride: May increase the sedative effects of Zopiclone.
Medications for Anxiety or Depression: Combining Zopiclone with anxiety or antidepressant medications can increase sedation, leading to drowsiness and impairing motor skills.
Medications for Epilepsy
If you are taking carbamazepine, a common medication for epilepsy, Zopiclone may interact with it, potentially enhancing side effects or reducing Zopiclone’s effectiveness. Always consult your doctor before combining these medications.
Medications for Sleep Disorders
Combining Zopiclone with other sleep medications can be dangerous. Both Zopiclone and other sleep aids act as sedatives, which may increase the risk of excessive drowsiness, poor motor coordination, and sleepwalking. Speak to your healthcare provider before combining any sleep aids with Zopiclone.
Painkillers
Zopiclone can interact with opioid painkillers such as codeine and morphine, enhancing their sedative effects. This increases the risk of drowsiness, dizziness, and impaired judgment. Always check with your doctor before using Zopiclone alongside painkillers.
Antidepressants
When combined with antidepressants such as SSRIs (e.g., fluoxetine) or SNRIs, Zopiclone may lead to an increased sedative effect, resulting in daytime drowsiness or difficulty concentrating. Be sure to consult your doctor before using Zopiclone with antidepressants.
Does Zopiclone Interact with Alcohol?
Yes, combining Zopiclone with alcohol can significantly increase the sedative effects of both substances. This can cause profound drowsiness, dizziness, and a loss of coordination, which can impair your ability to perform tasks such as driving or operating machinery. For your safety, it is recommended to avoid alcohol while taking Zopiclone. If you must drink alcohol, ensure it is in moderation and consult your healthcare provider for personalised advice.
Does Zopiclone Interact with Food?
Zopiclone can be taken with or without food, according to NHS guidelines. However, it is important to swallow the tablet whole and avoid crushing or chewing it, as this can affect the way the medication works. Always follow your doctor’s instructions regarding the best way to take Zopiclone for maximum effectiveness.
How Should You Take Zopiclone?
Zopiclone is typically taken once a day, just before bedtime. It is important to never exceed the prescribed dosage, as this could increase the risk of side effects. Zopiclone is not intended for long-term use, and your doctor will guide you on how long to use the medication.
Do I Need a Prescription for Zopiclone?
Yes, Zopiclone is a prescription-only medication. This means that you cannot purchase Zopiclone without a prescription from a registered healthcare professional. If you have trouble sleeping and think Zopiclone may be right for you, speak to your doctor, who can assess your condition and offer guidance on appropriate treatments.
Should You Speak to Your Doctor Before Taking Zopiclone?
Yes, before starting Zopiclone, it is essential to speak to your doctor or pharmacist, especially if you are currently taking other medications. You should inform them about:
Any medication for anxiety, depression, or sleep disorders.
Painkillers (particularly opioids).
Antibiotics or antifungal treatments.
Medications for epilepsy or mental health conditions.
Alcohol consumption.
Your doctor will be able to help you understand any potential interactions and advise on the safest course of action for combining Zopiclone with other medications.
Final Thoughts
Zopiclone is an effective treatment for insomnia, but it’s crucial to be aware of its interactions with other medications, alcohol, and food. Always consult your healthcare provider before combining Zopiclone with any other treatments to ensure your safety and to avoid unwanted side effects. Following the correct dosage and instructions, and staying in communication with your doctor, will help you use Zopiclone safely and effectively.
Medically Reviewed by:
Dr. Irfan Siddique MBBS
GMC reference no: 7694522
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